Herpes Virus, Potential Drug Candidates for Breast and
Ovarian Cancer
The team of Italian scientists
discovered a potential treatment for breast and ovarian cancer treatment. They
successfully developed a genetically engineered herpes virus to block the
spread of breast and ovarian cancer. Scientists believe that the virus is no
longer programmed harm humans and forms the basis for the treatment of cancer
in the future.
Herpes simplex virus (HSV) will
attack aggressive breast and ovarian tumors, which have more than one active
Her-2 gene. Engineered viruses injected in mice with breast and ovarian tumors,
significantly able to inhibit the spread of cancer cells. Or metastatic spread
of cancer, as reported by Huffingtonpost.com, is the leading cause of death in
cancer patients.
Professor Gabriella
Campadelli-Fiume, lead investigator from the University of Bologna Italy, said,
"Many laboratories around the world that use the virus as a weapon to
attack specific cancer cells called onkolitik virus."
According to him, in addition to
patient safety issues in the use of viruses onkolitik, various clinical studies
suggest the virus onkolitik only effective in a minority of tumors. "Our
study is the first that reprogrammed herpes virus to enter tumor cells and
infect other cells while maintaining the capacity of the destruction of the
herpes simplex virus."
The study, reported in the online
journal Public Library of Science Pathogens viral load that prevents the spread
of tumors through the abdominal cavity. Although the spread of cancer to the
ovary and the brain is reduced, the herpes virus is not able to protect the
lungs from cancer.
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